CATH Domain 6howB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Pteridine reductase

Enzyme Information

UniProtKB Entries (1)

O76290_TRYBB

Trypanosoma brucei brucei

Pteridine reductase

PDB Structure

PDB	6HOW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Insights into the Development of Cycloguanil Derivatives asTrypanosoma bruceiPteridine-Reductase-1 Inhibitors. Landi, G., Linciano, P., Borsari, C., Bertolacini, C.P., Moraes, C.B., Cordeiro-da-Silva, A., Gul, S., Witt, G., Kuzikov, M., Costi, M.P., Pozzi, C., Mangani, S. Acs Infect Dis.