CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | KRAS proto-oncogene, GTPase |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
| PDB | 6H46 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.
Nat Commun
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