CATH Domain 6fgbA02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	IgG receptor FcRn large subunit p51

Enzyme Information

UniProtKB Entries (1)

FCGRN_HUMAN

Homo sapiens

IgG receptor FcRn large subunit p51

PDB Structure

PDB	6FGB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. Smith, B., Kiessling, A., Lledo-Garcia, R., Dixon, K.L., Christodoulou, L., Catley, M.C., Atherfold, P., D'Hooghe, L.E., Finney, H., Greenslade, K., Hailu, H., Kevorkian, L., Lightwood, D., Meier, C., Munro, R., Qureshi, O., Sarkar, K., Shaw, S.P., Tewari, R., Turner, A., Tyson, K., West, S., Shaw, S., Brennan, F.R. MAbs