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1 keywords

CATH Domain 6fd4A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Adenine phosphoribosyltransferase

Enzyme Information

2.4.2.7
Adenine phosphoribosyltransferase.
based on mapping to UniProt P07741
AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- 5-amino-4-imidazolecarboxamide can replace adenine.

UniProtKB Entries (1)

P07741
APT_HUMAN
Homo sapiens
Adenine phosphoribosyltransferase

PDB Structure

PDB 6FD4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Huyet, J., Ozeir, M., Burgevin, M.C., Pinson, B., Chesney, F., Remy, J.M., Siddiqi, A.R., Lupoli, R., Pinon, G., Saint-Marc, C., Gibert, J.F., Morales, R., Ceballos-Picot, I., Barouki, R., Daignan-Fornier, B., Olivier-Bandini, A., Auge, F., Nioche, P.
Cell Chem Biol
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