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1 keywords

CATH Domain 6f7iB02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.3360  

Domain Context

CATH Clusters

Superfamily 2.60.40.3360
Functional Family Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Enzyme Information

3.4.22.-
Cysteine endopeptidases.
based on mapping to UniProt Q9UDY8

UniProtKB Entries (1)

Q9UDY8
MALT1_HUMAN
Homo sapiens
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

PDB Structure

PDB 6F7I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient.
Quancard, J., Klein, T., Fung, S.Y., Renatus, M., Hughes, N., Israel, L., Priatel, J.J., Kang, S., Blank, M.A., Viner, R.I., Blank, J., Schlapbach, A., Erbel, P., Kizhakkedathu, J., Villard, F., Hersperger, R., Turvey, S.E., Eder, J., Bornancin, F., Overall, C.M.
Nat. Chem. Biol.
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