CATH Domain 6enqB00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Peroxisome proliferator-activated receptor gamma

Enzyme Information

UniProtKB Entries (1)

PPARG_HUMAN

Homo sapiens

Peroxisome proliferator-activated receptor gamma

PDB Structure

PDB	6ENQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) alpha / gamma / delta Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate. Boubia, B., Poupardin, O., Barth, M., Binet, J., Peralba, P., Mounier, L., Jacquier, E., Gauthier, E., Lepais, V., Chatar, M., Ferry, S., Thourigny, A., Guillier, F., Llacer, J., Amaudrut, J., Dodey, P., Lacombe, O., Masson, P., Montalbetti, C., Wettstein, G., Luccarini, J.M., Legendre, C., Junien, J.L., Broqua, P. J. Med. Chem.