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1 keywords

CATH Domain 6el9A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Androgen receptor variant

Enzyme Information

UniProtKB Entries (1)

P04150
GCR_HUMAN
Homo sapiens
Glucocorticoid receptor

PDB Structure

PDB 6EL9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile.
Ripa, L., Edman, K., Dearman, M., Edenro, G., Hendrickx, R., Ullah, V., Chang, H.F., Lepisto, M., Chapman, D., Geschwindner, S., Wissler, L., Svanberg, P., Lawitz, K., Malmberg, J., Nikitidis, A., Olsson, R.I., Bird, J., Llinas, A., Hegelund-Myrback, T., Berger, M., Thorne, P., Harrison, R., Kohler, C., Drmota, T.
J. Med. Chem.
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