×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.160.20
Functional Family tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform X1

Enzyme Information

1.3.1.91
tRNA-dihydrouridine(20) synthase (NAD(P)(+)).
based on mapping to UniProt Q9NX74
5,6-dihydrouracil(20) in tRNA + NAD(P)(+) = uracil(20) in tRNA + NAD(P)H.
-!- The enzyme specifically modifies uracil(20) in tRNA.

UniProtKB Entries (1)

Q9NX74
DUS2L_HUMAN
Homo sapiens
TRNA-dihydrouridine(20) synthase [NAD(P)+]-like

PDB Structure

PDB 6EI8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformational Stability Adaptation of a Double-Stranded RNA-Binding Domain to Transfer RNA Ligand.
Bou-Nader, C., Pecqueur, L., Barraud, P., Fontecave, M., Tisne, C., Sacquin-Mora, S., Hamdane, D.
Biochemistry
CATH-Gene3D is a Global Biodata Core Resource Learn more...