CATH Domain 6ds6A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.60	Wheat Germ Agglutinin (Isolectin 2); domain 1
	3.30.60.90	Zinc finger, ZZ-type

Domain Context

CATH Clusters

Superfamily	3.30.60.90
Functional Family	E1A binding protein p300

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q09472 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q09472

UniProtKB Entries (1)

EP300_HUMAN

Homo sapiens

Histone acetyltransferase p300

PDB Structure

PDB	6DS6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3. Zhang, Y., Xue, Y., Shi, J., Ahn, J., Mi, W., Ali, M., Wang, X., Klein, B.J., Wen, H., Li, W., Shi, X., Kutateladze, T.G. Nat. Struct. Mol. Biol.