CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.870 | Son of sevenless (SoS) protein; Chain S, domain 1 | |
1.20.870.10 | Son of sevenless (SoS) protein Chain: S domain 1 |
Domain Context
CATH Clusters
Superfamily | Son of sevenless (SoS) protein Chain: S domain 1 |
Functional Family | son of sevenless homolog 1 isoform X1 |
Enzyme Information
UniProtKB Entries (1)
P01112 |
RASH_HUMAN
Homo sapiens
GTPase HRas
|
PDB Structure
PDB | 6BVL |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
J. Med. Chem.
|