CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1360 | Gyrase A; domain 2 | |
3.30.1360.10 | RNA polymerase, RBP11-like subunit |
Domain Context
CATH Clusters
Superfamily | RNA polymerase, RBP11-like subunit |
Functional Family | DNA-directed RNA polymerase subunit alpha |
Enzyme Information
2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt P0A7Z4
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (1)
P0A800 |
RPOZ_ECOLI
Escherichia coli K-12
DNA-directed RNA polymerase subunit omega
|
PDB Structure
PDB | 6ASX |
External Links | |
Method | ELECTRON MICROSCOPY |
Organism | |
Primary Citation |
RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.
Mol. Cell
|