×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (2)

P01112
RASH_HUMAN
Homo sapiens
GTPase HRas
Q9QZQ1
AFAD_MOUSE
Mus musculus
Afadin

PDB Structure

PDB 6AMB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith, M.J., Ottoni, E., Ishiyama, N., Goudreault, M., Haman, A., Meyer, C., Tucholska, M., Gasmi-Seabrook, G., Menezes, S., Laister, R.C., Minden, M.D., Marschalek, R., Gingras, A.C., Hoang, T., Ikura, M.
Nat Commun
CATH-Gene3D is a Global Biodata Core Resource Learn more...