CATH Domain 5y2fA01

Superfamily	TPP-binding domain
Functional Family	NAD-dependent protein deacetylase sirtuin-6

3.5.1.-

In linear amides.

based on mapping to UniProt Q8N6T7

SIR6_HUMAN

Homo sapiens

NAD-dependent protein deacetylase sirtuin-6

PDB	5Y2F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of a cellularly active SIRT6 allosteric activator. Huang, Z., Zhao, J., Deng, W., Chen, Y., Shang, J., Song, K., Zhang, L., Wang, C., Lu, S., Yang, X., He, B., Min, J., Hu, H., Tan, M., Xu, J., Zhang, Q., Zhong, J., Sun, X., Mao, Z., Lin, H., Xiao, M., Chin, Y.E., Jiang, H., Xu, Y., Chen, G., Zhang, J. Nat. Chem. Biol.