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1 keywords

CATH Domain 5x6rB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.50 3-Layer(bba) Sandwich
Topology 3.50.50 FAD/NAD(P)-binding domain
Homologous Superfamily 3.50.50.60 FAD/NAD(P)-binding domain

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family Kynurenine 3-monooxygenase

Enzyme Information

1.14.13.9
Kynurenine 3-monooxygenase.
based on mapping to UniProt P38169
L-kynurenine + NADPH + O(2) = 3-hydroxy-L-kynurenine + NADP(+) + H(2)O.
-!- Formerly EC 1.14.1.2 and EC 1.99.1.5.

UniProtKB Entries (1)

P38169
KMO_YEAST
Saccharomyces cerevisiae S288C
Kynurenine 3-monooxygenase

PDB Structure

PDB 5X6R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Kim, H.T., Na, B.K., Chung, J., Kim, S., Kwon, S.K., Cha, H., Son, J., Cho, J.M., Hwang, K.Y.
Cell Chem Biol
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