CATH Domain 5v4bB02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.10	YVTN repeat-like/Quinoprotein amine dehydrogenase

Domain Context

CATH Clusters

Superfamily	YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family	F-box/WD repeat-containing protein 7 isoform X1

Enzyme Information

UniProtKB Entries (1)

FBXW7_HUMAN

Homo sapiens

F-box/WD repeat-containing protein 7

PDB Structure

PDB	5V4B
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Yalla, K., Elliott, C., Day, J.P., Findlay, J., Barratt, S., Hughes, Z.A., Wilson, L., Whiteley, E., Popiolek, M., Li, Y., Dunlop, J., Killick, R., Adams, D.R., Brandon, N.J., Houslay, M.D., Hao, B., Baillie, G.S. Mol. Psychiatry