CATH Domain 5uppA02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.200	Fumarase C; Chain A, domain 2
	1.20.200.10	Fumarase/aspartase (Central domain)

Domain Context

CATH Clusters

Superfamily	Fumarase/aspartase (Central domain)
Functional Family	Fumarate hydratase, mitochondrial

Enzyme Information

4.2.1.2

Fumarate hydratase.

based on mapping to UniProt P07954

(S)-malate = fumarate + H(2)O.

UniProtKB Entries (1)

FUMH_HUMAN

Homo sapiens

Fumarate hydratase, mitochondrial

PDB Structure

PDB	5UPP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural, biochemical and biophysical characterization of recombinant human fumarate hydratase. Ajalla Aleixo, M.A., Rangel, V.L., Rustiguel, J.K., de Padua, R.A.P., Nonato, M.C. Febs J.