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1 keywords

CATH Domain 5ug6A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.150 C2 domain

Domain Context

CATH Clusters

Superfamily C2 domain
Functional Family Perforin-1 precursor

Enzyme Information

UniProtKB Entries (1)

P10820
PERF_MOUSE
Mus musculus
Perforin-1

PDB Structure

PDB 5UG6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.
Brennan, A.J., Law, R.H.P., Conroy, P.J., Noori, T., Lukoyanova, N., Saibil, H., Yagita, H., Ciccone, A., Verschoor, S., Whisstock, J.C., Trapani, J.A., Voskoboinik, I.
Cell Death Differ.
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