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1 keywords

CATH Domain 5udyA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.720 Alkaline Phosphatase, subunit A
Homologous Superfamily 3.40.720.10 Alkaline Phosphatase, subunit A

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family ectonucleotide pyrophosphatase/phosphodiesterase family member 7

Enzyme Information

3.1.4.12
Sphingomyelin phosphodiesterase.
based on mapping to UniProt Q6UWV6
Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
-!- Has very little activity on phosphatidylcholine.

UniProtKB Entries (1)

Q6UWV6
ENPP7_HUMAN
Homo sapiens
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

PDB Structure

PDB 5UDY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition.
Gorelik, A., Liu, F., Illes, K., Nagar, B.
J. Biol. Chem.
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