CATH Domain 5u0kE00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.20	Ankyrin repeat-containing domain

Domain Context

CATH Clusters

Superfamily	Ankyrin repeat-containing domain
Functional Family	Glutaminase liver isoform, mitochondrial

Enzyme Information

3.5.1.2

Glutaminase.

based on mapping to UniProt Q9UI32

L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

GLSL_HUMAN

Homo sapiens

Glutaminase liver isoform, mitochondrial

PDB Structure

PDB	5U0K
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. Pasquali, C.C., Islam, Z., Adamoski, D., Ferreira, I.M., Righeto, R.D., Bettini, J., Portugal, R.V., Yue, W.W., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B. J. Biol. Chem.