CATH Domain 5tvqA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.10	Deoxyribonuclease I; Chain A
	3.60.10.10	Endonuclease/exonuclease/phosphatase

Domain Context

CATH Clusters

Superfamily	Endonuclease/exonuclease/phosphatase
Functional Family	Tyrosyl-DNA phosphodiesterase 2

Enzyme Information

3.1.4.-

Phosphoric diester hydrolases.

based on mapping to UniProt Q9JJX7

UniProtKB Entries (1)

TYDP2_MOUSE

Mus musculus

Tyrosyl-DNA phosphodiesterase 2

PDB Structure

PDB	5TVQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links. Schellenberg, M.J., Lieberman, J.A., Herrero-Ruiz, A., Butler, L.R., Williams, J.G., Munoz-Cabello, A.M., Mueller, G.A., London, R.E., Cortes-Ledesma, F., Williams, R.S. Science