CATH Domain 5trlH00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.30	Gcn5-related N-acetyltransferase (GNAT)

Domain Context

CATH Clusters

Superfamily	3.40.630.30
Functional Family	Histone acetyltransferase KAT2A

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q92830 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q92830

UniProtKB Entries (1)

KAT2A_HUMAN

Homo sapiens

Histone acetyltransferase KAT2A

PDB Structure

PDB	5TRL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase. Wang, Y., Guo, Y.R., Liu, K., Yin, Z., Liu, R., Xia, Y., Tan, L., Yang, P., Lee, J.H., Li, X.J., Hawke, D., Zheng, Y., Qian, X., Lyu, J., He, J., Xing, D., Tao, Y.J., Lu, Z. Nature