CATH Domain 5tkkL01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin kappa variable 4-1

Enzyme Information

UniProtKB Entries (1)

ENV_HV1H2

HIV-1 M:B_HXB2R

Envelope glycoprotein gp160

PDB Structure

PDB	5TKK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Xu, K., Acharya, P., Kong, R., Cheng, C., Chuang, G.Y., Liu, K., Louder, M.K., O'Dell, S., Rawi, R., Sastry, M., Shen, C.H., Zhang, B., Zhou, T., Asokan, M., Bailer, R.T., Chambers, M., Chen, X., Choi, C.W., Dandey, V.P., Doria-Rose, N.A., Druz, A., Eng, E.T., Farney, S.K., Foulds, K.E., Geng, H., Georgiev, I.S., Gorman, J., Hill, K.R., Jafari, A.J., Kwon, Y.D., Lai, Y.T., Lemmin, T., McKee, K., Ohr, T.Y., Ou, L., Peng, D., Rowshan, A.P., Sheng, Z., Todd, J.P., Tsybovsky, Y., Viox, E.G., Wang, Y., Wei, H., Yang, Y., Zhou, A.F., Chen, R., Yang, L., Scorpio, D.G., McDermott, A.B., Shapiro, L., Carragher, B., Potter, C.S., Mascola, J.R., Kwong, P.D. Nat. Med.