CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.720 | Alkaline Phosphatase, subunit A |
|
3.40.720.10 | Alkaline Phosphatase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Alkaline Phosphatase, subunit A |
| Functional Family | ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
Enzyme Information
| 3.1.4.12 |
Sphingomyelin phosphodiesterase.
based on mapping to UniProt Q6UWV6
Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
-!- Has very little activity on phosphatidylcholine.
|
UniProtKB Entries (1)
| Q6UWV6 |
ENPP7_HUMAN
Homo sapiens
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
|
PDB Structure
| PDB | 5TCD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition.
J. Biol. Chem.
|
