CATH Domain 5t4uA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 1

Enzyme Information

UniProtKB Entries (1)

BRPF1_HUMAN

Homo sapiens

Peregrin

PDB Structure

PDB	5T4U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies. Igoe, N., Bayle, E.D., Fedorov, O., Tallant, C., Savitsky, P., Rogers, C., Owen, D.R., Deb, G., Somervaille, T.C., Andrews, D.M., Jones, N., Cheasty, A., Ryder, H., Brennan, P.E., Muller, S., Knapp, S., Fish, P.V. J. Med. Chem.