CATH Domain 5o2dA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.220	Leucine Aminopeptidase, subunit E; domain 1
	3.40.220.10	Leucine Aminopeptidase, subunit E, domain 1

Domain Context

CATH Clusters

Superfamily	Leucine Aminopeptidase, subunit E, domain 1
Functional Family	Poly [ADP-ribose] polymerase

Enzyme Information

2.4.2.-

Pentosyltransferases.

based on mapping to UniProt Q460N5

UniProtKB Entries (1)

PAR14_HUMAN

Homo sapiens

Protein mono-ADP-ribosyltransferase PARP14

PDB Structure

PDB	5O2D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14. Schuller, M., Riedel, K., Gibbs-Seymour, I., Uth, K., Sieg, C., Gehring, A.P., Ahel, I., Bracher, F., Kessler, B.M., Elkins, J.M., Knapp, S. ACS Chem. Biol.