CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | ABC transporter ATP-binding protein |
Enzyme Information
| 7.5.2.5 |
ABC-type lipopolysaccharide transporter.
based on mapping to UniProt Q0P9C4
ATP + H(2)O + lipopolysaccharide(Side 1) = ADP + phosphate + lipopolysaccharide(Side 2).
-!- An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. -!- Does not undergo phosphorylation during the transport process. -!- The enzyme, characterized from the bacterium Escherichia coli, functions as part of the lipopolysaccharide (LPS) export system, a seven protein system that translocates LPS from the inner- to the outer membrane. -!- The ATPase activity in this system is implicated in releasing LPS from the inner membrane. -!- Formerly EC 3.6.3.39.
|
UniProtKB Entries (1)
| Q0P9C4 |
PGLK_CAMJE
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Protein glycosylation K
|
PDB Structure
| PDB | 5NBD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.
Sci Rep
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