CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.1700 | Protein-arginine deiminase, central domain |
Domain Context
CATH Clusters
Superfamily | Protein-arginine deiminase, central domain |
Functional Family | Protein-arginine deiminase type-2 |
Enzyme Information
3.5.3.15 |
Protein-arginine deiminase.
based on mapping to UniProt Q9UM07
Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
-!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.
|
UniProtKB Entries (1)
Q9UM07 |
PADI4_HUMAN
Homo sapiens
Protein-arginine deiminase type-4
|
PDB Structure
PDB | 5N1B |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Development of a Selective Inhibitor of Protein Arginine Deiminase 2.
J. Med. Chem.
|