CATH Domain 5malB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1110	SGNH hydrolase

Domain Context

CATH Clusters

Superfamily	SGNH hydrolase
Functional Family	Lipase 1

Enzyme Information

3.1.2.2	Palmitoyl-CoA hydrolase. based on mapping to UniProt Q93MW7 Palmitoyl-CoA + H(2)O = CoA + palmitate. -!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.
3.1.1.3	Triacylglycerol lipase. based on mapping to UniProt Q93MW7 Triacylglycerol + H(2)O = diacylglycerol + a carboxylate. -!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
3.1.1.-	Carboxylic ester hydrolases. based on mapping to UniProt Q93MW7

UniProtKB Entries (1)

LIP_STRRM

Streptomyces rimosus

Lipase

PDB Structure

PDB	5MAL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Catalytic Dyad in the SGNH Hydrolase Superfamily: In-depth Insight into Structural Parameters Tuning the Catalytic Process of Extracellular Lipase from Streptomyces rimosus. Lescic Asler, I., Stefanic, Z., Marsavelski, A., Vianello, R., Kojic-Prodic, B. ACS Chem. Biol.