CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
Superfamily | alpha/beta hydrolase |
Functional Family | Platelet-activating factor acetylhydrolase |
Enzyme Information
3.1.1.47 |
1-alkyl-2-acetylglycerophosphocholine esterase.
based on mapping to UniProt Q13093
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.
|
UniProtKB Entries (1)
Q13093 |
PAFA_HUMAN
Homo sapiens
Platelet-activating factor acetylhydrolase
|
PDB Structure
PDB | 5LZ7 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).
J. Med. Chem.
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