CATH Domain 5ls6C01

Superfamily
Functional Family	-

PDB	5LS6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas. Vaswani, R.G., Gehling, V.S., Dakin, L.A., Cook, A.S., Nasveschuk, C.G., Duplessis, M., Iyer, P., Balasubramanian, S., Zhao, F., Good, A.C., Campbell, R., Lee, C., Cantone, N., Cummings, R.T., Normant, E., Bellon, S.F., Albrecht, B.K., Harmange, J.C., Trojer, P., Audia, J.E., Zhang, Y., Justin, N., Chen, S., Wilson, J.R., Gamblin, S.J. J. Med. Chem.