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1 keywords

CATH Domain 5l6yC00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.1250 Growth Hormone; Chain: A;
Homologous Superfamily 1.20.1250.10  

Domain Context

CATH Clusters

Superfamily 1.20.1250.10
Functional Family Interleukin-13

Enzyme Information

UniProtKB Entries (1)

P35225
IL13_HUMAN
Homo sapiens
Interleukin-13

PDB Structure

PDB 5L6Y
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2.
Popovic, B., Breed, J., Rees, D.G., Gardener, M.J., Vinall, L.M., Kemp, B., Spooner, J., Keen, J., Minter, R., Uddin, F., Colice, G., Wilkinson, T., Vaughan, T., May, R.D.
J. Mol. Biol.
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