CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.410 | Factor Xa Inhibitor |
|
4.10.410.20 |
Domain Context
CATH Clusters
| Superfamily | 4.10.410.20 |
| Functional Family | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
Enzyme Information
| 3.1.4.39 |
Alkylglycerophosphoethanolamine phosphodiesterase.
based on mapping to UniProt Q13822
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
-!- Also acts on acyl and choline analogs.
|
UniProtKB Entries (1)
| Q13822 |
ENPP2_HUMAN
Homo sapiens
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
|
PDB Structure
| PDB | 5KXA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis.
J. Pharmacol. Exp. Ther.
|
