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1 keywords

CATH Domain 5kr1A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

V5YAB1
V5YAB1_9HIV1
Human immunodeficiency virus 1
Pol protein

PDB Structure

PDB 5KR1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution.
Liu, Z., Huang, X., Hu, L., Pham, L., Poole, K.M., Tang, Y., Mahon, B.P., Tang, W., Li, K., Goldfarb, N.E., Dunn, B.M., McKenna, R., Fanucci, G.E.
J.Biol.Chem.
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