CATH Domain 5k1vB01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1730	tricorn interacting facor f3 domain

Domain Context

CATH Clusters

Superfamily	tricorn interacting facor f3 domain
Functional Family	Endoplasmic reticulum aminopeptidase 2

Enzyme Information

3.4.11.-

Aminopeptidases.

based on mapping to UniProt Q6P179

UniProtKB Entries (1)

ERAP2_HUMAN

Homo sapiens

Endoplasmic reticulum aminopeptidase 2

PDB Structure

PDB	5K1V
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency. Mpakali, A., Giastas, P., Deprez-Poulain, R., Papakyriakou, A., Koumantou, D., Gealageas, R., Tsoukalidou, S., Vourloumis, D., Mavridis, I.M., Stratikos, E., Saridakis, E. ACS Med Chem Lett