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CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1280.50
Functional Family F-box and WD repeat domain-containing 7

Enzyme Information

UniProtKB Entries (1)

Q969H0
FBXW7_HUMAN
Homo sapiens
F-box/WD repeat-containing protein 7

PDB Structure

PDB 5IBK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.
Gorelik, M., Orlicky, S., Sartori, M.A., Tang, X., Marcon, E., Kurinov, I., Greenblatt, J.F., Tyers, M., Moffat, J., Sicheri, F., Sidhu, S.S.
Proc.Natl.Acad.Sci.USA
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