CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family | 17-beta-hydroxysteroid dehydrogenase 14 |
Enzyme Information
1.1.1.- |
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9BPX1
|
UniProtKB Entries (1)
Q9BPX1 |
DHB14_HUMAN
Homo sapiens
17-beta-hydroxysteroid dehydrogenase 14
|
PDB Structure
PDB | 5HS6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor.
J.Med.Chem.
|