CATH Domain 5ettB00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.560	7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK

Domain Context

CATH Clusters

Superfamily	7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q2G0Q5_STAA8

Staphylococcus aureus subsp. aureus NCTC 8325

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

PDB Structure

PDB	5ETT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. Dennis, M.L., Pitcher, N.P., Lee, M.D., DeBono, A.J., Wang, Z.C., Harjani, J.R., Rahmani, R., Cleary, B., Peat, T.S., Baell, J.B., Swarbrick, J.D. J.Med.Chem.