CATH Domain 5emlB00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.10	YVTN repeat-like/Quinoprotein amine dehydrogenase

Domain Context

CATH Clusters

Superfamily	YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family	Methylosome protein 50

Enzyme Information

UniProtKB Entries (1)

MEP50_HUMAN

Homo sapiens

Methylosome protein 50

PDB Structure

PDB	5EML
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. Duncan, K.W., Rioux, N., Boriack-Sjodin, P.A., Munchhof, M.J., Reiter, L.A., Majer, C.R., Jin, L., Johnston, L.D., Chan-Penebre, E., Kuplast, K.G., Porter Scott, M., Pollock, R.M., Waters, N.J., Smith, J.J., Moyer, M.P., Copeland, R.A., Chesworth, R. ACS Med Chem Lett