CATH Domain 5dwuB02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Cytokine receptor common subunit beta

Enzyme Information

UniProtKB Entries (1)

IL3RB_HUMAN

Homo sapiens

Cytokine receptor common subunit beta

PDB Structure

PDB	5DWU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors. Panousis, C., Dhagat, U., Edwards, K.M., Rayzman, V., Hardy, M.P., Braley, H., Gauvreau, G.M., Hercus, T.R., Smith, S., Sehmi, R., McMillan, L., Dottore, M., McClure, B.J., Fabri, L.J., Vairo, G., Lopez, A.F., Parker, M.W., Nash, A.D., Wilson, N.J., Wilson, M.J., Owczarek, C.M. Mabs