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1 keywords

CATH Domain 5dtjB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P21836
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P21836
ACES_MOUSE
Mus musculus
Acetylcholinesterase

PDB Structure

PDB 5DTJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.
Katz, F.S., Pecic, S., Tran, T.H., Trakht, I., Schneider, L., Zhu, Z., Ton-That, L., Luzac, M., Zlatanic, V., Damera, S., Macdonald, J., Landry, D.W., Tong, L., Stojanovic, M.N.
Chembiochem
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