CATH Domain 5anlA01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.70	Phosphatidylinositol 3-kinase, accessory domain (PIK)

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase, accessory domain (PIK)
Functional Family	Phosphatidylinositol 3-kinase catalytic subunit type 3

Enzyme Information

2.7.1.137

Phosphatidylinositol 3-kinase.

based on mapping to UniProt Q8NEB9

ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo- inositol 3-phosphate.

UniProtKB Entries (1)

PK3C3_HUMAN

Homo sapiens

Phosphatidylinositol 3-kinase catalytic subunit type 3

PDB Structure

PDB	5ANL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Automated Harvesting and Processing of Protein Crystals Through Laser Photoablation. Zander, U., Hoffmann, G., Cornaciu, I., Marquette, J.-P., Papp, G., Landret, C., Seroul, G., Sinoir, J., Roewer, M., Felisaz, F., Rodriguez-Puente, S., Mariaule, V., Murphy, P., Mathieu, M., Cipriani, F., Marquez, J.A. Acta Crystallogr.,Sect.D