×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4yonA01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.900 Dbl Homology Domain; Chain A
Homologous Superfamily 1.20.900.10 Dbl homology (DH) domain

Domain Context

CATH Clusters

Superfamily Dbl homology (DH) domain
Functional Family Phosphatidylinositol-3,4, 5-trisphosphate-dependent Rac exchange factor 2, putative

Enzyme Information

UniProtKB Entries (1)

P63000
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1

PDB Structure

PDB 4YON
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
Lucato, C.M., Halls, M.L., Ooms, L.M., Liu, H.J., Mitchell, C.A., Whisstock, J.C., Ellisdon, A.M.
J.Biol.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...