CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1360 | Gyrase A; domain 2 |
|
3.30.1360.20 | Transcriptional coactivator/pterin dehydratase |
Domain Context
CATH Clusters
| Superfamily | Transcriptional coactivator/pterin dehydratase |
| Functional Family | Pterin-4-alpha-carbinolamine dehydratase 2 |
Enzyme Information
| 4.2.1.96 |
4a-hydroxytetrahydrobiopterin dehydratase.
based on mapping to UniProt Q9CZL5
(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro- 4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro- 6H-pterin + H(2)O.
-!- Catalyzes the dehydration of 4a-hydroxytetrahydrobiopterins.
|
UniProtKB Entries (1)
| Q9CZL5 |
PHS2_MOUSE
Mus musculus
Pterin-4-alpha-carbinolamine dehydratase 2
|
PDB Structure
| PDB | 4WIL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Interactions with the Bifunctional Interface of the Transcriptional Coactivator DCoH1 Are Kinetically Regulated.
J.Biol.Chem.
|
