CATH Domain 4uitA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Putative bromodomain-containing protein 9

Enzyme Information

UniProtKB Entries (1)

BRD9_HUMAN

Homo sapiens

Bromodomain-containing protein 9

PDB Structure

PDB	4UIT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition. Theodoulou, N.H., Bamborough, P., Bannister, A.J., Becher, I., Bit, R.A., Che, K.H., Chung, C., Dittmann, A., Drewes, G., Drewry, D.H., Gordon, L., Grandi, P., Leveridge, M., Lindon, M., Michon, A., Molnar, J., Robson, S.C., Tomkinson, N.C.O., Kouzarides, T., Prinjha, R.K., Humphreys, P.G. J.Med.Chem.