CATH Domain 4tvqD02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.330	Nucleotidyltransferases domain 2

Domain Context

CATH Clusters

Superfamily	Nucleotidyltransferases domain 2
Functional Family	Programmed cell death protein 10

Enzyme Information

UniProtKB Entries (1)

CCM2_HUMAN

Homo sapiens

Cerebral cavernous malformations 2 protein

PDB Structure

PDB	4TVQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation. Draheim, K.M., Li, X., Zhang, R., Fisher, O.S., Villari, G., Boggon, T.J., Calderwood, D.A. J.Cell Biol.