×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4rugB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.30 SH3 type barrels.
Homologous Superfamily 2.30.30.40 SH3 Domains

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family SLIT-ROBO Rho GTPase-activating protein 2

Enzyme Information

UniProtKB Entries (1)

O75044
SRGP2_HUMAN
Homo sapiens
SLIT-ROBO Rho GTPase-activating protein 2

PDB Structure

PDB 4RUG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Guez-Haddad, J., Sporny, M., Sasson, Y., Gevorkyan-Airapetov, L., Lahav-Mankovski, N., Margulies, D., Radzimanowski, J., Opatowsky, Y.
Structure
CATH-Gene3D is a Global Biodata Core Resource Learn more...