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1 keywords

CATH Domain 4rf0A03

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.1680  

Domain Context

CATH Clusters

Superfamily 2.60.120.1680
Functional Family Polyprotein ORF1ab

Enzyme Information

UniProtKB Entries (2)

P62987
RL40_HUMAN
Homo sapiens
Ubiquitin-60S ribosomal protein L40
M4STU1
M4STU1_9BETC
Human betacoronavirus 2c Jordan-N3/2012
ORF1ab protein

PDB Structure

PDB 4RF0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
Bailey-Elkin, B.A., Knaap, R.C., Johnson, G.G., Dalebout, T.J., Ninaber, D.K., van Kasteren, P.B., Bredenbeek, P.J., Snijder, E.J., Kikkert, M., Mark, B.L.
J.Biol.Chem.
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