CATH Domain 4rdaA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.770	Amyloid precursor protein, E2 domain

Domain Context

CATH Clusters

Superfamily	Amyloid precursor protein, E2 domain
Functional Family	Amyloid beta A4 protein-like isoform 1

Enzyme Information

UniProtKB Entries (1)

APLP1_HUMAN

Homo sapiens

Amyloid-like protein 1

PDB Structure

PDB	4RDA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes. Dahms, S.O., Mayer, M.C., Roeser, D., Multhaup, G., Than, M.E. Acta Crystallogr.,Sect.D