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1 keywords

CATH Domain 4r43A01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.449 Phosphoenolpyruvate Carboxykinase; domain 1
Homologous Superfamily 3.40.449.10 Phosphoenolpyruvate Carboxykinase, domain 1

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate Carboxykinase, domain 1
Functional Family Phosphoenolpyruvate carboxykinase [GTP]

Enzyme Information

4.1.1.32
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P9WIH3
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.

UniProtKB Entries (1)

P9WIH3
PCKG_MYCTU
Mycobacterium tuberculosis H37Rv
Phosphoenolpyruvate carboxykinase [GTP]

PDB Structure

PDB 4R43
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Functional Studies of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis.
Machova, I., Snasel, J., Dostal, J., Brynda, J., Fanfrlik, J., Singh, M., Tarabek, J., Vanek, O., Bednarova, L., Pichova, I.
Plos One
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