×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4ovuB02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.287 Helix Hairpins
Homologous Superfamily 1.10.287.1490  

Domain Context

CATH Clusters

Superfamily 1.10.287.1490
Functional Family Putative phosphatidylinositol 3-kinase regulatory subunit alpha

Enzyme Information

UniProtKB Entries (1)

P42336
PK3CA_HUMAN
Homo sapiens
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

PDB Structure

PDB 4OVU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of nSH2 regulation and lipid binding in PI3K alpha.
Miller, M.S., Schmidt-Kittler, O., Bolduc, D.M., Brower, E.T., Chaves-Moreira, D., Allaire, M., Kinzler, K.W., Jennings, I.G., Thompson, P.E., Cole, P.A., Amzel, L.M., Vogelstein, B., Gabelli, S.B.
Oncotarget
CATH-Gene3D is a Global Biodata Core Resource Learn more...